We have received an SC2 grant from the NIGMS of NIH for 3 years to work on the simplex retina of the little skate. The grant, titled “Structural and molecular determinants of duplex functionality in a pure-rod retina”, will support our investigation of the mechanisms of functional adaptation in the naturally-occurring monotypic photoreceptor retina of L. erinacea. Results from this work could hold the key to expanding the functional repertoire of surviving photoreceptors in diseased duplex retinae and consequently lead to novel approaches in therapeutic vision restoration efforts.